Director of Cell Therapy, In Vitro Pharmacology
Company: Takeda Pharmaceutical
Location: Boston
Posted on: October 30, 2024
Job Description:
By clicking the "Apply" button, I understand that my employment
application process with Takeda will commence and that the
information I provide in my application will be processed in line
with Takeda's and . I further attest that all information I submit
in my employment application is true to the best of my
knowledge.Job DescriptionAbout the role:At Takeda, we are a
forward-looking, world-class R&D organization that unlocks
innovation and delivers transformative therapies to patients. By
focusing R&D efforts on four therapeutic areas and other
targeted investments, we push the boundaries of what is possible in
order to bring life-changing therapies to patients worldwide.Join
Takeda as a Director of Cell Therapy where you will lead a team
responsible for designing and implementing in vitro pharmacological
assays, using state-of-the-art technologies and methodologies,
leading the discovery of novel Cell Therapy products, and
contributing to the strategic direction of our Cell Therapy
research programs. As part of the Vitro Pharmacology team, you will
report to the Head of the team and be a highly skilled and
experienced leader.How you will contribute:
- Strategic Leadership: Provide strategic direction and
leadership for the Cell Therapy in vitro pharmacology team,
ensuring alignment with company goals and objectives. Develop and
implement innovative strategies to support the discovery and
development of novel therapies.
- Functional Leadership: Lead the design, development,
optimization, and execution of high-quality in vitro pharmacology
assays to evaluate the activity, mechanism of action, and efficacy
of Cell Therapy products. Use cutting-edge technologies and
methodologies to assess immune cell function and tumor-immune
interactions. Develop and implement strategies to enhance the in
vitro pharmacology capabilities and throughput. Stay up to date
with the latest scientific advancements and industry trends.
- Program Leadership: Lead the Cell Therapy discovery programs
with cross-functional teams, driving the programs from lead ID to
preclinical development.
- Candidates Screening and Profiling: Oversee the screening and
profiling of Cell Therapy candidates in relevant in vitro models
including immune cell-based assays, co-culture systems, and 3D
organoid models. Evaluate candidate efficacy, potency and
selectivity, to support lead optimization and candidate
selection.
- Mechanism of Action Studies: Investigate the molecular
mechanisms underlying the activity of Cell Therapy candidates using
in vitro pharmacology approaches.
- Cross-functional Collaboration: Collaborate closely with
interdisciplinary discovery teams in a matrix format, including
biologics engineering, biologics production, analytics,
translational scientists, and preclinical development teams to
advance discovery programs. Communicate results effectively and
contribute to project team meetings, scientific discussions, and
project planning activities.
- Mentoring: Mentor and develop junior scientists, fostering a
culture of innovation, collaboration, and scientific
excellence.Minimum Requirements/Qualifications:
- PhD degree in immunology, cancer biology, or a related field
with 10+ years experience , or MS with 16+ years experience, or BS
with 18+ years experience.
- Minimum of 10 years of experience in Cell Therapy research,
with a focus on immune cell biology, and tumor-immune
interactions.
- Minimum of 7 years of management experience.
- Expertise in drug discovery and development processes,
including hit identification, lead optimization, candidate
selection, and preclinical development.
- Proven track record of leading successful in vitro pharmacology
efforts in the field of Cell Therapy, including assay development
and validation, candidate screening, and mechanism of action
studies.
- Strong technical proficiency in a wide range of in vitro
pharmacology techniques and assay formats.
- Excellent leadership, communication, and interpersonal skills,
with the ability to lead a team and projects and collaborate
effectively across disciplines, demonstrate enterprise leadership
with an ability to influence without authority.
- Knowledge of regulatory requirements and guidelines for drug
discovery and development.More about us:At Takeda, we are
transforming patient care through the development of novel
specialty pharmaceuticals and best in class patient support
programs. Takeda is a patient-focused company that will inspire and
empower you to grow through life-changing work.Certified as a
Global Top Employer, Takeda offers stimulating careers, encourages
innovation, and strives for excellence in everything we do. We
foster an inclusive, collaborative workplace, in which our teams
are united by an unwavering commitment to deliver Better Health and
a Brighter Future to people around the
world.#LI-SGM#LI-OnsiteTakeda Compensation and Benefits SummaryWe
understand compensation is an important factor as you consider the
next step in your career. We are committed to equitable pay for all
employees, and we strive to be more transparent with our pay
practices. -For Location:Boston, MAU.S. Base Salary
Range:$169,400.00 - $266,200.00The estimated salary range reflects
an anticipated range for this position. The actual base salary
offered may depend on a variety of factors, including the
qualifications of the individual applicant for the position, years
of relevant experience, specific and unique skills, level of
education attained, certifications or other professional licenses
held, and the location in which the applicant lives and/or from
which they will be performing the job.---The actual base salary
offered will be in accordance with state or local minimum wage
requirements for the job location. -U.S. based employees may be
eligible for short-term and/ or long-term incentives. U.S. based
employees may be eligible to participate in medical, dental, vision
insurance, a 401(k) plan and company match, short-term and
long-term disability coverage, basic life insurance, a tuition
reimbursement program, paid volunteer time off, company holidays,
and well-being benefits, among others. U.S. based employees are
also eligible to receive, per calendar year, up to 80 hours of sick
time, and new hires are eligible to accrue up to 120 hours of paid
vacation. -EEO StatementTakeda is proud in its commitment to
creating a diverse workforce and providing equal employment
opportunities to all employees and applicants for employment
without regard to race, color, religion, sex, sexual orientation,
gender identity, gender expression, parental status, national
origin, age, disability, citizenship status, genetic information or
characteristics, marital status, status as a Vietnam era veteran,
special disabled veteran, or other protected veteran in accordance
with applicable federal, state and local laws, and any other
characteristic protected by law.LocationsBoston, MAWorker
TypeEmployeeWorker Sub-TypeRegularTime TypeFull time
Keywords: Takeda Pharmaceutical, Hartford , Director of Cell Therapy, In Vitro Pharmacology, Executive , Boston, Connecticut
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